Universitätsklinikum Carl Gustav Carus Dresden and the Technische Universität Dresden

    Foundation year2006
    DirectorProf. Dr. Dr. Hagen B. Huttner; Prof. Dr. Marius Ader
    Principal investigatorPD Dr. med. René Günther; Prof. Dr. Jared Sterneckert

    The University Outpatient Clinic for Motor Neurone Diseases at the University Hospital Carl Gustav Carus Dresden serves patients with amyotrophic lateral sclerosis and its variants, spinal muscular atrophy, hereditary spastic spinal paralysis and other motor neurone diseases. We offer diagnostic classification (including electrophysiology, imaging procedures, lumbar puncture with biomarker analysis, etc.), second opinion and multidisciplinary therapy support for patients with motor neurone diseases. Our centre has vast experience delivering gene therapeutics (nusinersen, risdiplam and tofersen). In addition to patient care, scientific research is important to us. Patients at our centre are, therefore, invited to participate in clinical trials of drug candidates as well as research studies, which currently focus on biomarker research, treatment efficacy and drug treatment side effects as well as on the improvement of palliative patient care.

    The Technische Universität Dresden, particularly at the Center for Regenerative Therapies TU Dresden (CRTD), utilizes patient-derived induced pluripotent stem (iPS) cells in combination with animal models to identify molecular mechanisms of disease pathogenesis as well as novel therapeutic targets to treat motor neurone diseases.

    Contact Information

    AddressDresdenFetscherstraße 10501307 Germany

    ContactUniversitätsklinikum Carl Gustav Carus Dresden and the Technische Universität Dresden

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    Serving population
    150 milion

    Patient resources

    Population based register
    Clinic based register
    Geographically matched controls

    Banks

    Research activities

    Clinical management research
    Neuro epidemiology
    Neuro physiology
    Neuro imaging
    Neuro psychology
    Neuro pathology
    Genomics
    Transcriptomics
    Metabolomics

    Publication

    Search for publications of Jared Sterneckert and René Günther.