National ALS Clinic based at Beaumont Hospital Dublin, providing a multidisciplinary service to the entire Irish ALS population. Academic centre at Trinity College Dublin Clinical research in epidemiology, cognition, genetics and biomarkers, and laboratory based research in bioinformatics and drug development.
| Irish ALS Research Group | |
|---|---|
| Foundation year | 1994 |
| Director | Professor Orla Hardiman |
| Principal investigator | Professor Orla Hardiman |
| Contact information | |
|---|---|
| Address | TCD Biomedical Sciences Institute, |
| Contact | Dr. O. Hardiman |
| Phone | +35318964497 |
| hardimao@tcd.ie | |
| Website | Visit the website |
Publications
- Byrne S, Elamin M, Bede P, Hardiman O. Absence of consensus in diagnostic criteria for familial neurodegenerative diseases. J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):365-7. PubMed PMID: 22399794.
- Bede P, Bokde AL, Byrne S, Elamin M, Fagan AJ, Hardiman O. Spinal cord markers in ALS: Diagnostic and biomarker considerations. Amyotroph Lateral Scler. 2012 Feb 13. [Epub ahead of print] PubMed PMID: 22329869.
- Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O\’Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol. 2012 Mar;11(3):232-40. Epub 2012 Feb 3. Erratum in: Lancet Neurol. 2012 May;11(5):388. PubMed PMID: 22305801; PubMed Central PMCID: PMC3315021.
- Foley G, Timonen V, Hardiman O. Experience of Services as a Key Outcome in Amyotrophic Lateral Sclerosis (ALS) Care: The Case for a Better Understanding of Patient Experiences. Am J Hosp Palliat Care. 2011 Oct 13. [Epub ahead of print] PubMed PMID: 21998444.
- Hardiman O, van den Berg LH, Kiernan MC. Clinical diagnosis and management of amyotrophic lateral sclerosis. Nat Rev Neurol. 2011 Oct 11;7(11):639-49. doi: 10.1038/nrneurol.2011.153. Review. PubMed PMID: 21989247.
Restricted information
| Serving population | |
|---|---|
| Serving population | 4.7 million |
| Patient resources | |
|---|---|
| Population based register | Yes |
| Clinic based register | Yes |
| Geographically matched controls | Yes |
| Number of brain samples | Ongoing |
| Number of IPS cell samples | Ongoing |
Banks
| Type | ALS Patients | Controls | Other |
|---|---|---|---|
| DNA Bank | 0 | 0 | 0 |
| RNA Bank | 0 | 0 | 0 |
| Research activities | |
|---|---|
| Clinical management research | Yes |
| Neuro epidemiology | Yes |
| Neuro physiology | Yes |
| Neuro imaging | Yes |
| Neuro psychology | Yes |
| Neuro pathology | Yes |
| Genomics | Yes |
| Transcriptomics | No |
| Metabolomics | No |
Clinical Trials - Industry sponsored
| Name | Type | Patients |
|---|---|---|
| EMPOWER | EMPOWER | 24 |
Clinical Trials - Investigator initiated
There are no clinical trials for this centre