Tricals

    Irish ALS Research Group

    Foundation year1994
    DirectorProfessor Orla Hardiman
    Principal investigatorProfessor Orla Hardiman

    National ALS Clinic based at Beaumont Hospital Dublin, providing a multidisciplinary service to the entire Irish ALS population. Academic centre at Trinity College Dublin Clinical research in epidemiology, cognition, genetics and biomarkers, and laboratory based research in bioinformatics and drug development.

    Contact Information

    AddressDublinPearse StreetDublin 2 Ireland

    ContactDr. O. Hardiman

    Phone35318964497
    Emailhardimao@tcd.ie
    Website

    Restricted information

    Serving population
    4.7 million

    Patient resources

    Population based register
    Clinic based register
    Geographically matched controls
    Number of muscle samples
    0
    Number of skin samples
    0
    Number of spinal cord samples
    0
    Number of brain samples
    Ongoing
    Number of IPS cell samples
    Ongoing

    Banks

    TypeALS PatientsControlsOther
    DNA Bank
    0
    0
    0
    RNA Bank
    0
    0
    0
    Clinical management research
    Neuro epidemiology
    Neuro physiology
    Neuro imaging
    Neuro psychology
    Neuro pathology
    Genomics
    Transcriptomics
    Metabolomics

    Publication

    • Byrne S, Elamin M, Bede P, Hardiman O. Absence of consensus in diagnostic criteria for familial neurodegenerative diseases. J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):365-7. PubMed PMID: 22399794.
    • Bede P, Bokde AL, Byrne S, Elamin M, Fagan AJ, Hardiman O. Spinal cord markers in ALS: Diagnostic and biomarker considerations. Amyotroph Lateral Scler. 2012 Feb 13. [Epub ahead of print] PubMed PMID: 22329869.
    • Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O\’Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol. 2012 Mar;11(3):232-40. Epub 2012 Feb 3. Erratum in: Lancet Neurol. 2012 May;11(5):388. PubMed PMID: 22305801; PubMed Central PMCID: PMC3315021.
    • Foley G, Timonen V, Hardiman O. Experience of Services as a Key Outcome in Amyotrophic Lateral Sclerosis (ALS) Care: The Case for a Better Understanding of Patient Experiences. Am J Hosp Palliat Care. 2011 Oct 13. [Epub ahead of print] PubMed PMID: 21998444.
    • Hardiman O, van den Berg LH, Kiernan MC. Clinical diagnosis and management of amyotrophic lateral sclerosis. Nat Rev Neurol. 2011 Oct 11;7(11):639-49. doi: 10.1038/nrneurol.2011.153. Review. PubMed PMID: 21989247.