Irish ALS Research Group

Foundation year1994
DirectorProfessor Orla Hardiman
Principal investigatorProfessor Orla Hardiman

National ALS Clinic based at Beaumont Hospital Dublin, providing a multidisciplinary service to the entire Irish ALS population. Academic centre at Trinity College Dublin Clinical research in epidemiology, cognition, genetics and biomarkers, and laboratory based research in bioinformatics and drug development.

Contact Information

AddressDublinPearse StreetDublin 2 Ireland

ContactDr. O. Hardiman

Phone35318964497
Emailhardimao@tcd.ie
Website

Restricted information

Serving population
4.7 million

Patient resources

Population based register
Clinic based register
Geographically matched controls
Number of muscle samples
0
Number of skin samples
0
Number of spinal cord samples
0
Number of brain samples
Ongoing
Number of IPS cell samples
Ongoing

Banks

TypeALS PatientsControlsOther
DNA Bank
0
0
0
RNA Bank
0
0
0
Clinical management research
Neuro epidemiology
Neuro physiology
Neuro imaging
Neuro psychology
Neuro pathology
Genomics
Transcriptomics
Metabolomics

Publication

  • Byrne S, Elamin M, Bede P, Hardiman O. Absence of consensus in diagnostic criteria for familial neurodegenerative diseases. J Neurol Neurosurg Psychiatry. 2012 Apr;83(4):365-7. PubMed PMID: 22399794.
  • Bede P, Bokde AL, Byrne S, Elamin M, Fagan AJ, Hardiman O. Spinal cord markers in ALS: Diagnostic and biomarker considerations. Amyotroph Lateral Scler. 2012 Feb 13. [Epub ahead of print] PubMed PMID: 22329869.
  • Byrne S, Elamin M, Bede P, Shatunov A, Walsh C, Corr B, Heverin M, Jordan N, Kenna K, Lynch C, McLaughlin RL, Iyer PM, O\’Brien C, Phukan J, Wynne B, Bokde AL, Bradley DG, Pender N, Al-Chalabi A, Hardiman O. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study. Lancet Neurol. 2012 Mar;11(3):232-40. Epub 2012 Feb 3. Erratum in: Lancet Neurol. 2012 May;11(5):388. PubMed PMID: 22305801; PubMed Central PMCID: PMC3315021.
  • Foley G, Timonen V, Hardiman O. Experience of Services as a Key Outcome in Amyotrophic Lateral Sclerosis (ALS) Care: The Case for a Better Understanding of Patient Experiences. Am J Hosp Palliat Care. 2011 Oct 13. [Epub ahead of print] PubMed PMID: 21998444.
  • Hardiman O, van den Berg LH, Kiernan MC. Clinical diagnosis and management of amyotrophic lateral sclerosis. Nat Rev Neurol. 2011 Oct 11;7(11):639-49. doi: 10.1038/nrneurol.2011.153. Review. PubMed PMID: 21989247.